Fever-induced epileptic encephalopathy in children (FIRES)

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Elevated VGKC-complex antibodies in a boy with fever-induced refractory epileptic encephalopathy in school-age children (FIRES).

Fever-induced refractory epileptic encephalopathy in school-age children (FIRES) is a clinically recognized epileptic encephalopathy of unknown aetiology. Presentation in previously healthy children is characterized by febrile status epilepticus. A pharmacoresistant epilepsy ensues, occurring in parallel with dramatic cognitive decline and behavioural difficulties. We describe a case of FIRES i...

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18F-FDG PET reveals frontotemporal dysfunction in children with fever-induced refractory epileptic encephalopathy.

UNLABELLED Fever-induced refractory epileptic encephalopathy in school-age children (FIRES) is a recently described epileptic entity whose etiology remains unknown. Brain abnormalities shown by MRI are usually limited to mesial-temporal structures and do not account for the catastrophic neuropsychologic findings. METHODS We conducted FIRES studies in 8 patients, aged 6-13 y, using 18F-FDG PET...

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Epileptic encephalopathies are conditions in which epileptic activity itself is postulated to contribute to severe cognitive and behavioural impairments above and beyond what might be expected from the underlying pathology alone. The term has been used in two ways: (1) as a generic classification term for epilepsies with severe cognitive and be-havioural outcomes and (2) as a pathophysiological...

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ژورنال

عنوان ژورنال: HERALD of North-Western State Medical University named after I.I. Mechnikov

سال: 2019

ISSN: 2618-9704,2618-7116

DOI: 10.17816/mechnikov201810465-72